ea0090p472 | Reproductive and Developmental Endocrinology | ECE2023
Akmador Nahudan
, Barrera Jerome
Background: Idiopathic hypogonadotropic hypogonadism (IHH) is manifested as absent or incomplete puberty and biochemically low levels of sex hormones, with low or inappropriately normal gonadotropin hormones. In the absence of structural or functional lesions of the hypothalamic or pituitary gland, the hypogonadism is referred as idiopathic hypogonadotropic hypogonadism (IHH). IHH is a genetically heterogeneous disorder which can be caused by pathogenic variants affecting prot...